NUP214 Break Apart FISH Probe
Empire Genomics’ NUP214 Break Apart FISH Probe is designed to flank the NUP214 gene and is typically used for detecting NUP214 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
NUP214BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
NUP214BA-20-AQOR | 20 (40 μL) | 200 μL | ||
NUP214BA-20-GOGR | 20 (40 μL) | 200 μL | ||
NUP214BA-20-GORE | 20 (40 μL) | 200 μL | ||
NUP214BA-20-GRGO | 20 (40 μL) | 200 μL | ||
NUP214BA-20-GROR | 20 (40 μL) | 200 μL | ||
NUP214BA-20-GRRE | 20 (40 μL) | 200 μL | ||
NUP214BA-20-REGO | 20 (40 μL) | 200 μL | ||
NUP214BA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene is a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is localized to the cytoplasmic face of the nuclear pore complex where it is required for proper cell cycle progression and nucleocytoplasmic transport. The 3' portion of this gene forms a fusion gene with the DEK gene on chromosome 6 in a t(6,9) translocation associated with acute myeloid leukemia and myelodysplastic syndrome. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
Gene Details
Gene Symbol: NUP214
Gene Name: Nucleoporin 214
Chromosome: CHR9: 134000980-134109091
Locus: 9q34.13
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|
Customer Publications
Product Details
Product: NUP214 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NUP214-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping