NUDT1 FISH Probe
The NUDT1 FISH probe is designed to hybridize to the NUDT1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NUDT1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| NUDT1-20-RE | 20 (40 μL) | 200 μL |  |
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| NUDT1-20-GO | 20 (40 μL) | 200 μL |  |
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| NUDT1-20-GR | 20 (40 μL) | 200 μL |  |
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| NUDT1-20-AQ | 20 (40 μL) | 200 μL |  |
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| NUDT1-20-DIG | 20 (40 μL) | 200 μL |  |
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| NUDT1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation. The encoded protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Several alternatively spliced transcript variants, some of which encode distinct isoforms, have been identified. Additional variants have been observed, but their full-length natures have not been determined. A single-nucleotide polymorphism that results in the production of an additional, longer isoform (p26) has been described. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: NUDT1
Gene Name: Nudix Hydrolase 1
Chromosome: CHR7: 2281856-2290780
Locus: 7p22.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: NUDT1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NUDT1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping