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NTRK3 Break Apart FISH Probe

Empire Genomics’ NTRK3 Break Apart FISH Probe is designed to flank the NTRK3 gene and is typically used for detecting NTRK3 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping
Download Datasheet Download FISH Protocol Download Material Safety Data Sheet

SKU Test Kits Buffer Dye Color Order Now
NTRK3BA-20-GROR  (Standard Design) 20 (40 μL) 200 μL
NTRK3BA-20-AQOR 20 (40 μL) 200 μL
NTRK3BA-20-GOGR 20 (40 μL) 200 μL
NTRK3BA-20-GORE 20 (40 μL) 200 μL
NTRK3BA-20-GRGO 20 (40 μL) 200 μL
NTRK3BA-20-GRRE 20 (40 μL) 200 μL
NTRK3BA-20-ORGR 20 (40 μL) 200 μL
NTRK3BA-20-REGO 20 (40 μL) 200 μL
NTRK3BA-20-REGR 20 (40 μL) 200 μL

Gene Summary

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]

Gene Details

Gene Symbol: NTRK3

Gene Name: Neurotrophic Receptor Tyrosine Kinase 3

Chromosome: CHR15: 88419987-88799962

Locus: 15q25.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Identification of NTRK3 Fusions in Childhood Melanocytic Neoplasms

Our NTRK3 break apart probes were used to detect NTRK3 rearrangements in spitzoid neoplasms, a subtype of melanocytic tumors characterized by an absence of typical melanoma-associated mutations. Four of the patients tested positive for NTRK3 translocations, including a novel MYO5A-NTRK3 fusion.
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Product Details

Product: NTRK3 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: NTRK3-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping