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NTRK3 FISH Probe

The NTRK3 FISH probe is designed to hybridize to the NTRK3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

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Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping
Download Datasheet Download FISH Protocol Download Material Safety Data Sheet

SKU Test Kits Buffer Dye Color Order Now
NTRK3-20-OR  (Standard Design) 20 (40 μL) 200 μL
NTRK3-20-RE 20 (40 μL) 200 μL
NTRK3-20-GO 20 (40 μL) 200 μL
NTRK3-20-GR 20 (40 μL) 200 μL
NTRK3-20-AQ 20 (40 μL) 200 μL
NTRK3-20-DIG 20 (40 μL) 200 μL
NTRK3-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]

Gene Details

Gene Symbol: NTRK3

Gene Name: Neurotrophic Receptor Tyrosine Kinase 3

Chromosome: CHR15: 88419987-88799962

Locus: 15q25.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Identification of NTRK3 Fusions in Childhood Melanocytic Neoplasms

Our NTRK3 break apart probes were used to detect NTRK3 rearrangements in spitzoid neoplasms, a subtype of melanocytic tumors characterized by an absence of typical melanoma-associated mutations. Four of the patients tested positive for NTRK3 translocations, including a novel MYO5A-NTRK3 fusion.
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Product Details

Product: NTRK3 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: NTRK3-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping