NSMCE2 Break Apart FISH Probe
Empire Genomics’ NSMCE2 Break Apart FISH Probe is designed to flank the NSMCE2 gene and is typically used for detecting NSMCE2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NSMCE2BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NSMCE2BA-20-AQOR | 20 (40 μL) | 200 μL |
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| NSMCE2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| NSMCE2BA-20-GORE | 20 (40 μL) | 200 μL |
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| NSMCE2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| NSMCE2BA-20-GROR | 20 (40 μL) | 200 μL |
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| NSMCE2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| NSMCE2BA-20-REGO | 20 (40 μL) | 200 μL |
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| NSMCE2BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of a family of E3 small ubiquitin-related modifier (SUMO) ligases that mediates the attachment of a SUMO protein to proteins involved in nuclear transport, transcription, chromosome segregation and DNA repair. The encoded protein is part of the structural maintenance of chromosomes (SMC) 5/6 complex which plays a key role genome maintenance, facilitating chromosome segregation and suppressing mitotic recombination. A knockout of the orthologous mouse gene is lethal prior to embryonic day 10.5. Naturally occurring mutations in this gene, that abolish the SUMO ligase activity, are associated with primordial dwarfism and extreme insulin resistance. [provided by RefSeq, Mar 2017]
Gene Details
Gene Symbol: NSMCE2
Gene Name: NSE2/MMS21 Homolog, SMC5-SMC6 Complex SUMO Ligase
Chromosome: CHR8: 126104082-126379367
Locus: 8q24.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: NSMCE2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NSMCE2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping