NSMCE2 FISH Probe
The NSMCE2 FISH probe is designed to hybridize to the NSMCE2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NSMCE2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| NSMCE2-20-RE | 20 (40 μL) | 200 μL |  |
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| NSMCE2-20-GO | 20 (40 μL) | 200 μL |  |
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| NSMCE2-20-GR | 20 (40 μL) | 200 μL |  |
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| NSMCE2-20-AQ | 20 (40 μL) | 200 μL |  |
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| NSMCE2-20-DIG | 20 (40 μL) | 200 μL |  |
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| NSMCE2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of a family of E3 small ubiquitin-related modifier (SUMO) ligases that mediates the attachment of a SUMO protein to proteins involved in nuclear transport, transcription, chromosome segregation and DNA repair. The encoded protein is part of the structural maintenance of chromosomes (SMC) 5/6 complex which plays a key role genome maintenance, facilitating chromosome segregation and suppressing mitotic recombination. A knockout of the orthologous mouse gene is lethal prior to embryonic day 10.5. Naturally occurring mutations in this gene, that abolish the SUMO ligase activity, are associated with primordial dwarfism and extreme insulin resistance. [provided by RefSeq, Mar 2017]
Gene Details
Gene Symbol: NSMCE2
Gene Name: NSE2/MMS21 Homolog, SMC5-SMC6 Complex SUMO Ligase
Chromosome: CHR8: 126104082-126379367
Locus: 8q24.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: NSMCE2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NSMCE2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping