NSD1 FISH Probe
The NSD1 FISH probe is designed to hybridize to the NSD1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NSD1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| NSD1-20-RE | 20 (40 μL) | 200 μL |  |
|
| NSD1-20-GO | 20 (40 μL) | 200 μL |  |
|
| NSD1-20-GR | 20 (40 μL) | 200 μL |  |
|
| NSD1-20-AQ | 20 (40 μL) | 200 μL |  |
|
| NSD1-20-DIG | 20 (40 μL) | 200 μL |  |
|
| NSD1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: NSD1
Gene Name: Nuclear Receptor Binding SET Domain Protein 1
Chromosome: CHR5: 176560079-176727214
Locus: 5q35.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: NSD1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NSD1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping