NRXN1 FISH Probe
The NRXN1 FISH probe is designed to hybridize to the NRXN1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
NRXN1-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
NRXN1-20-RE | 20 (40 μL) | 200 μL | ||
NRXN1-20-GO | 20 (40 μL) | 200 μL | ||
NRXN1-20-GR | 20 (40 μL) | 200 μL | ||
NRXN1-20-AQ | 20 (40 μL) | 200 μL | ||
NRXN1-20-DIG | 20 (40 μL) | 200 μL | ||
NRXN1-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca(2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3,000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for this gene in the 3' region. Mutations in this gene are associated with Pitt-Hopkins-like syndrome-2 and may contribute to susceptibility to schizophrenia. [provided by RefSeq, Aug 2016]
Gene Details
Gene Symbol: NRXN1
Gene Name: Neurexin 1
Chromosome: CHR2: 50145642-51259674
Locus: 2p16.3
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: NRXN1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NRXN1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping