NR1I2 Break Apart FISH Probe
Empire Genomics’ NR1I2 Break Apart FISH Probe is designed to flank the NR1I2 gene and is typically used for detecting NR1I2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NR1I2BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NR1I2BA-20-AQOR | 20 (40 μL) | 200 μL |
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| NR1I2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| NR1I2BA-20-GORE | 20 (40 μL) | 200 μL |
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| NR1I2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| NR1I2BA-20-GROR | 20 (40 μL) | 200 μL |
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| NR1I2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| NR1I2BA-20-REGO | 20 (40 μL) | 200 μL |
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| NR1I2BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: NR1I2
Gene Name: Nuclear Receptor Subfamily 1 Group I Member 2
Chromosome: CHR3: 119499330-119537332
Locus: 3q13.33
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: NR1I2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NR1I2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping