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NR1I2 FISH Probe

The NR1I2 FISH probe is designed to hybridize to the NR1I2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
NR1I2-20-OR  (Standard Design) 20 (40 μL) 200 μL
NR1I2-20-RE 20 (40 μL) 200 μL
NR1I2-20-GO 20 (40 μL) 200 μL
NR1I2-20-GR 20 (40 μL) 200 μL
NR1I2-20-AQ 20 (40 μL) 200 μL
NR1I2-20-DIG 20 (40 μL) 200 μL
NR1I2-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: NR1I2

Gene Name: Nuclear Receptor Subfamily 1 Group I Member 2

Chromosome: CHR3: 119499330-119537332

Locus: 3q13.33

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: NR1I2 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: NR1I2-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping