NR1I2 FISH Probe
The NR1I2 FISH probe is designed to hybridize to the NR1I2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NR1I2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| NR1I2-20-RE | 20 (40 μL) | 200 μL |  |
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| NR1I2-20-GO | 20 (40 μL) | 200 μL |  |
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| NR1I2-20-GR | 20 (40 μL) | 200 μL |  |
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| NR1I2-20-AQ | 20 (40 μL) | 200 μL |  |
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| NR1I2-20-DIG | 20 (40 μL) | 200 μL |  |
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| NR1I2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: NR1I2
Gene Name: Nuclear Receptor Subfamily 1 Group I Member 2
Chromosome: CHR3: 119499330-119537332
Locus: 3q13.33
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: NR1I2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NR1I2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping