NR0B2 FISH Probe
The NR0B2 FISH probe is designed to hybridize to the NR0B2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NR0B2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| NR0B2-20-RE | 20 (40 μL) | 200 μL |  |
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| NR0B2-20-GO | 20 (40 μL) | 200 μL |  |
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| NR0B2-20-GR | 20 (40 μL) | 200 μL |  |
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| NR0B2-20-AQ | 20 (40 μL) | 200 μL |  |
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| NR0B2-20-DIG | 20 (40 μL) | 200 μL |  |
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| NR0B2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: NR0B2
Gene Name: Nuclear Receptor Subfamily 0 Group B Member 2
Chromosome: CHR1: 27237974-27240567
Locus: 1p36.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: NR0B2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NR0B2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping