NQO1 FISH Probe
The NQO1 FISH probe is designed to hybridize to the NQO1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NQO1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| NQO1-20-RE | 20 (40 μL) | 200 μL |  |
|
| NQO1-20-GO | 20 (40 μL) | 200 μL |  |
|
| NQO1-20-GR | 20 (40 μL) | 200 μL |  |
|
| NQO1-20-AQ | 20 (40 μL) | 200 μL |  |
|
| NQO1-20-DIG | 20 (40 μL) | 200 μL |  |
|
| NQO1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: NQO1
Gene Name: NAD(P)H Quinone Dehydrogenase 1
Chromosome: CHR16: 69743303-69760533
Locus: 16q22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: NQO1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NQO1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping