NPHN FISH Probe
The NPHN FISH probe is designed to hybridize to the NPHN gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NPHS1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| NPHS1-20-RE | 20 (40 μL) | 200 μL |  |
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| NPHS1-20-GO | 20 (40 μL) | 200 μL |  |
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| NPHS1-20-GR | 20 (40 μL) | 200 μL |  |
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| NPHS1-20-AQ | 20 (40 μL) | 200 μL |  |
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| NPHS1-20-DIG | 20 (40 μL) | 200 μL |  |
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| NPHS1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.[provided by RefSeq, Oct 2009]
Gene Details
Gene Symbol: NPHS1
Gene Name: NPHS1, Nephrin
Chromosome: CHR19: 36316273-36342895
Locus: 19q13.12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: NPHN FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NPHS1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping