NOTCH3 Break Apart FISH Probe
Empire Genomics’ NOTCH3 Break Apart FISH Probe is designed to flank the NOTCH3 gene and is typically used for detecting NOTCH3 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NOTCH3BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| NOTCH3BA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| NOTCH3BA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| NOTCH3BA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| NOTCH3BA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| NOTCH3BA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| NOTCH3BA-20-ORGR | 20 (40 μL) | 200 μL |
|
|
| NOTCH3BA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| NOTCH3BA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: NOTCH3
Gene Name: Notch 3
Chromosome: CHR19: 15270443-15311792
Locus: 19p13.12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: NOTCH3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NOTCH3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping