NOB1 FISH Probe
The NOB1 FISH probe is designed to hybridize to the NOB1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NOB1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| NOB1-20-RE | 20 (40 μL) | 200 μL |  |
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| NOB1-20-GO | 20 (40 μL) | 200 μL |  |
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| NOB1-20-GR | 20 (40 μL) | 200 μL |  |
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| NOB1-20-AQ | 20 (40 μL) | 200 μL |  |
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| NOB1-20-DIG | 20 (40 μL) | 200 μL |  |
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| NOB1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 [PubMed 19706509]).[supplied by OMIM, Nov 2010]
Gene Details
Gene Symbol: NOB1
Gene Name: NIN1/PSMD8 Binding Protein 1 Homolog
Chromosome: CHR16: 69775773-69788829
Locus: 16q22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: NOB1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NOB1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping