NLRP2 Break Apart FISH Probe
Empire Genomics’ NLRP2 Break Apart FISH Probe is designed to flank the NLRP2 gene and is typically used for detecting NLRP2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NLRP2BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NLRP2BA-20-AQOR | 20 (40 μL) | 200 μL |
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| NLRP2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| NLRP2BA-20-GORE | 20 (40 μL) | 200 μL |
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| NLRP2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| NLRP2BA-20-GROR | 20 (40 μL) | 200 μL |
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| NLRP2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| NLRP2BA-20-REGO | 20 (40 μL) | 200 μL |
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| NLRP2BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD), a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR). Members of this gene family are thought to be important regulators of immune responses. This gene product interacts with components of the IkB kinase (IKK) complex, and can regulate both caspase-1 and NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) activity. The pyrin domain is necessary and sufficient for suppression of NF-kB activity. An allelic variant (rs147585490) has been found that is incapable of blocking the transcriptional activity of NF-kB. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]
Gene Details
Gene Symbol: NLRP2
Gene Name: NLR Family Pyrin Domain Containing 2
Chromosome: CHR19: 55476651-55512510
Locus: 19q13.42
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: NLRP2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NLRP2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping