NKX2-1 FISH Probe
The NKX2-1 FISH probe is designed to hybridize to the NKX2-1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
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| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NKX2-1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| NKX2-1-20-RE | 20 (40 μL) | 200 μL |  |
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| NKX2-1-20-GO | 20 (40 μL) | 200 μL |  |
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| NKX2-1-20-GR | 20 (40 μL) | 200 μL |  |
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| NKX2-1-20-AQ | 20 (40 μL) | 200 μL |  |
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| NKX2-1-20-DIG | 20 (40 μL) | 200 μL |  |
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| NKX2-1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014]
Gene Details
Gene Symbol: NKX2-1
Gene Name: NK2 Homeobox 1
Chromosome: CHR14: 36985603-36989430
Locus: 14q13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: NKX2-1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NKX2-1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping