NK1 FISH Probe
The NK1 FISH probe is designed to hybridize to the NK1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CD160-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| CD160-20-RE | 20 (40 μL) | 200 μL |  |
|
| CD160-20-GO | 20 (40 μL) | 200 μL |  |
|
| CD160-20-GR | 20 (40 μL) | 200 μL |  |
|
| CD160-20-AQ | 20 (40 μL) | 200 μL |  |
|
| CD160-20-DIG | 20 (40 μL) | 200 μL |  |
|
| CD160-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: CD160
Gene Name: CD160 Molecule
Chromosome: CHR1: 145695797-145715565
Locus: 1q21.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: NK1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CD160-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping