NGS-17 FISH Probe
The NGS-17 FISH probe is designed to hybridize to the NGS-17 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TAPBP-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TAPBP-20-RE | 20 (40 μL) | 200 μL |  |
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| TAPBP-20-GO | 20 (40 μL) | 200 μL |  |
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| TAPBP-20-GR | 20 (40 μL) | 200 μL |  |
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| TAPBP-20-AQ | 20 (40 μL) | 200 μL |  |
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| TAPBP-20-DIG | 20 (40 μL) | 200 μL |  |
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| TAPBP-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: TAPBP
Gene Name: TAP Binding Protein
Chromosome: CHR6_qbl_hap6: 4499711-4514410
Locus: 6p21.32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: NGS-17 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TAPBP-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping