NF-E4 FISH Probe
The NF-E4 FISH probe is designed to hybridize to the NF-E4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NFE4-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| NFE4-20-RE | 20 (40 μL) | 200 μL |  |
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| NFE4-20-GO | 20 (40 μL) | 200 μL |  |
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| NFE4-20-GR | 20 (40 μL) | 200 μL |  |
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| NFE4-20-AQ | 20 (40 μL) | 200 μL |  |
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| NFE4-20-DIG | 20 (40 μL) | 200 μL |  |
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| NFE4-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The erythroid-specific protein encoded by this gene, and the ubiquitous transcription factor CP2, form the stage selector protein (SSP) complex, which is involved in preferential expression of the gamma-globin genes in fetal erythroid cells. Alternate use of an in-frame upstream non-AUG (CUG) translation initiation codon, and a downstream AUG codon, results in two isoforms. While the long isoform (22 kDa) acts as an activator, the short isoform (14 kDa) has been shown to repress gamma-globin gene expression. This gene is located in an intron of the FBXL13 gene on the opposite strand. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: NFE4
Gene Name: Nuclear Factor, Erythroid 4
Chromosome: CHR7: 102973436-102978666
Locus: 7q22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: NF-E4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NFE4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping