NEIL2 FISH Probe
The NEIL2 FISH probe is designed to hybridize to the NEIL2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NEIL2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| NEIL2-20-RE | 20 (40 μL) | 200 μL |  |
|
| NEIL2-20-GO | 20 (40 μL) | 200 μL |  |
|
| NEIL2-20-GR | 20 (40 μL) | 200 μL |  |
|
| NEIL2-20-AQ | 20 (40 μL) | 200 μL |  |
|
| NEIL2-20-DIG | 20 (40 μL) | 200 μL |  |
|
| NEIL2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the Fpg/Nei family of DNA glycosylases. These glycosylases initiate the first step in base excision repair by cleaving oxidatively damaged bases and introducing a DNA strand break via their abasic site lyase activity. This enzyme is primarily associated with DNA repair during transcription and acts prefentially on cytosine-derived lesions, particularly 5-hydroxyuracil and 5-hydroxycytosine. It contains an N-terminal catalytic domain, a hinge region, and a C-terminal DNA-binding domain with helix-two-turn-helix and zinc finger motifs. This enzyme interacts with the X-ray cross complementing factor 1 scaffold protein as part of a multi-protein DNA repair complex. A pseudogene of this gene has been identified. [provided by RefSeq, Mar 2017]
Gene Details
Gene Symbol: NEIL2
Gene Name: Nei Like DNA Glycosylase 2
Chromosome: CHR8: 11627171-11644854
Locus: 8p23.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: NEIL2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NEIL2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping