NEDD4L FISH Probe
The NEDD4L FISH probe is designed to hybridize to the NEDD4L gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NEDD4L-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| NEDD4L-20-RE | 20 (40 μL) | 200 μL |  |
|
| NEDD4L-20-GO | 20 (40 μL) | 200 μL |  |
|
| NEDD4L-20-GR | 20 (40 μL) | 200 μL |  |
|
| NEDD4L-20-AQ | 20 (40 μL) | 200 μL |  |
|
| NEDD4L-20-DIG | 20 (40 μL) | 200 μL |  |
|
| NEDD4L-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
Gene Details
Gene Symbol: NEDD4L
Gene Name: Neural Precursor Cell Expressed, Developmentally Down-regulated 4-like, E3 Ubiquitin Protein Ligase
Chromosome: CHR18: 55711609-56068772
Locus: 18q21.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: NEDD4L FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NEDD4L-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping