NDUFA1 FISH Probe
The NDUFA1 FISH probe is designed to hybridize to the NDUFA1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NDUFA1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| NDUFA1-20-RE | 20 (40 μL) | 200 μL |  |
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| NDUFA1-20-GO | 20 (40 μL) | 200 μL |  |
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| NDUFA1-20-GR | 20 (40 μL) | 200 μL |  |
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| NDUFA1-20-AQ | 20 (40 μL) | 200 μL |  |
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| NDUFA1-20-DIG | 20 (40 μL) | 200 μL |  |
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| NDUFA1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the "hydrophobic protein" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: NDUFA1
Gene Name: NADH:ubiquinone Oxidoreductase Subunit A1
Chromosome: CHRX: 119005733-119010629
Locus: Xq24
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: NDUFA1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NDUFA1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping