NBR2 Break Apart FISH Probe
Empire Genomics’ NBR2 Break Apart FISH Probe is designed to flank the NBR2 gene and is typically used for detecting NBR2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NBR2BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| NBR2BA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| NBR2BA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| NBR2BA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| NBR2BA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| NBR2BA-20-GROR | 20 (40 μL) | 200 μL |
|
|
| NBR2BA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| NBR2BA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| NBR2BA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
This gene was identified by its close proximity on chromosome 17 to tumor suppressor gene BRCA1. Experimental evidence indicates that the two genes share a bi-directional promoter. Transcription for either gene is controlled individually by distinct transcriptional repressor factors. A short (112 amino acid) open reading frame is observed which includes a region derived from a LINE1 element. A strong Kozak signal is not observed for the putative ORF and the stop codon is more than 55 nucleotides upstream of the last splice site for the transcript, suggesting that the transcript is subject to nonsense-mediated decay. Therefore, this gene does not appear to encode a protein. Glucose starvation induces the expression of this gene and the long non-coding RNA transcribed by it functions with AMP-activated protein kinase in mediating the energy stress response. [provided by RefSeq, Aug 2016]
Gene Details
Gene Symbol: NBR2
Gene Name: Neighbor Of BRCA1 Gene 2 (non-protein Coding)
Chromosome: CHR17: 41277599-41297125
Locus: 17q21.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: NBR2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NBR2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping