NALCN FISH Probe
The NALCN FISH probe is designed to hybridize to the NALCN gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NALCN-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| NALCN-20-RE | 20 (40 μL) | 200 μL |  |
|
| NALCN-20-GO | 20 (40 μL) | 200 μL |  |
|
| NALCN-20-GR | 20 (40 μL) | 200 μL |  |
|
| NALCN-20-AQ | 20 (40 μL) | 200 μL |  |
|
| NALCN-20-DIG | 20 (40 μL) | 200 μL |  |
|
| NALCN-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a voltage-independent, nonselective cation channel which belongs to a family of voltage-gated sodium and calcium channels that regulates the resting membrane potential and excitability of neurons. This family is expressed throughout the nervous system and conducts a persistent sodium leak current that contributes to tonic neuronal excitability. The encoded protein forms a channelosome complex that includes G-protein-coupled receptors, UNC-79, UNC-80, NCA localization factor-1, and src family tyrosine kinases. Naturally occurring mutations in this gene are associated with infantile neuroaxonal dystrophy, infantile hypotonia with psychomotor retardation and characteristic facies (IHPRF) syndrome, and congenital contractures of the limbs and face with hypotonia and developmental delay (CLIFAHDD) syndrome. A knockout of the orthologous gene in mice results in paralysis with a severely disrupted respiratory rhythm, and lethality within 24 hours after birth. [provided by RefSeq, Apr 2017]
Gene Details
Gene Symbol: NALCN
Gene Name: Sodium Leak Channel, Non-selective
Chromosome: CHR13: 101706129-102068813
Locus: 13q32.3-q33.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: NALCN FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NALCN-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping