NAGPA Break Apart FISH Probe
Empire Genomics’ NAGPA Break Apart FISH Probe is designed to flank the NAGPA gene and is typically used for detecting NAGPA rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NAGPABA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| NAGPABA-20-AQOR | 20 (40 μL) | 200 μL |
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| NAGPABA-20-GOGR | 20 (40 μL) | 200 μL |
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| NAGPABA-20-GORE | 20 (40 μL) | 200 μL |
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| NAGPABA-20-GRGO | 20 (40 μL) | 200 μL |
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| NAGPABA-20-GRRE | 20 (40 μL) | 200 μL |
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| NAGPABA-20-ORGR | 20 (40 μL) | 200 μL |
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| NAGPABA-20-REGO | 20 (40 μL) | 200 μL |
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| NAGPABA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
Hydrolases are transported to lysosomes after binding to mannose 6-phosphate receptors in the trans-Golgi network. This gene encodes the enzyme that catalyzes the second step in the formation of the mannose 6-phosphate recognition marker on lysosomal hydrolases. Commonly known as 'uncovering enzyme' or UCE, this enzyme removes N-acetyl-D-glucosamine (GlcNAc) residues from GlcNAc-alpha-P-mannose moieties and thereby produces the recognition marker. The encoded preproprotein is proteolytically processed by furin to generate the mature enzyme, a homotetramer of two disulfide-linked homodimers. Mutations in this gene are associated with developmental stuttering in human patients. [provided by RefSeq, Oct 2015]
Gene Details
Gene Symbol: NAGPA
Gene Name: N-acetylglucosamine-1-phosphodiester Alpha-N-acetylglucosaminidase
Chromosome: CHR16: 5074844-5083942
Locus: 16p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: NAGPA FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NAGPA-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping