NACA FISH Probe
The NACA FISH probe is designed to hybridize to the NACA gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
NACA-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
NACA-20-RE | 20 (40 μL) | 200 μL | ||
NACA-20-GO | 20 (40 μL) | 200 μL | ||
NACA-20-GR | 20 (40 μL) | 200 μL | ||
NACA-20-AQ | 20 (40 μL) | 200 μL | ||
NACA-20-DIG | 20 (40 μL) | 200 μL | ||
NACA-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different chromosomes. [provided by RefSeq, Feb 2016]
Gene Details
Gene Symbol: NACA
Gene Name: Nascent Polypeptide-associated Complex Alpha Subunit
Chromosome: CHR12: 57106210-57119326
Locus: 12q13.3
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|
Customer Publications
Product Details
Product: NACA FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NACA-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping