N312 FISH Probe
The N312 FISH probe is designed to hybridize to the N312 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ANXA7-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ANXA7-20-RE | 20 (40 μL) | 200 μL |  |
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| ANXA7-20-GO | 20 (40 μL) | 200 μL |  |
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| ANXA7-20-GR | 20 (40 μL) | 200 μL |  |
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| ANXA7-20-AQ | 20 (40 μL) | 200 μL |  |
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| ANXA7-20-DIG | 20 (40 μL) | 200 μL |  |
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| ANXA7-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: ANXA7
Gene Name: Annexin A7
Chromosome: CHR10: 75135188-75173841
Locus: 10q22.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: N312 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ANXA7-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping