MYC FISH Probe
The MYC FISH probe is designed to hybridize to the MYC gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
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| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MYC-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MYC-20-RE | 20 (40 μL) | 200 μL |  |
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| MYC-20-GO | 20 (40 μL) | 200 μL |  |
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| MYC-20-GR | 20 (40 μL) | 200 μL |  |
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| MYC-20-AQ | 20 (40 μL) | 200 μL |  |
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| MYC-20-DIG | 20 (40 μL) | 200 μL |  |
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| MYC-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: MYC
Gene Name: MYC Proto-oncogene, BHLH Transcription Factor
Chromosome: CHR8: 128748314-128753680
Locus: 8q24.21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MYC FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MYC-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping