MUTYH Break Apart FISH Probe
Empire Genomics’ MUTYH Break Apart FISH Probe is designed to flank the MUTYH gene and is typically used for detecting MUTYH rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MUTYHBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| MUTYHBA-20-AQOR | 20 (40 μL) | 200 μL |
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| MUTYHBA-20-GOGR | 20 (40 μL) | 200 μL |
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| MUTYHBA-20-GORE | 20 (40 μL) | 200 μL |
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| MUTYHBA-20-GRGO | 20 (40 μL) | 200 μL |
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| MUTYHBA-20-GRRE | 20 (40 μL) | 200 μL |
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| MUTYHBA-20-ORGR | 20 (40 μL) | 200 μL |
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| MUTYHBA-20-REGO | 20 (40 μL) | 200 μL |
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| MUTYHBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. This gene product is thought to play a role in signaling apoptosis by the introduction of single-strand breaks following oxidative damage. Mutations in this gene result in heritable predisposition to colorectal cancer, termed MUTYH-associated polyposis (MAP). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2017]
Gene Details
Gene Symbol: MUTYH
Gene Name: MutY DNA Glycosylase
Chromosome: CHR1: 45794913-45806142
Locus: 1p34.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MUTYH FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MUTYH-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping