MUTYH FISH Probe
The MUTYH FISH probe is designed to hybridize to the MUTYH gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MUTYH-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MUTYH-20-RE | 20 (40 μL) | 200 μL |  |
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| MUTYH-20-GO | 20 (40 μL) | 200 μL |  |
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| MUTYH-20-GR | 20 (40 μL) | 200 μL |  |
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| MUTYH-20-AQ | 20 (40 μL) | 200 μL |  |
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| MUTYH-20-DIG | 20 (40 μL) | 200 μL |  |
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| MUTYH-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. This gene product is thought to play a role in signaling apoptosis by the introduction of single-strand breaks following oxidative damage. Mutations in this gene result in heritable predisposition to colorectal cancer, termed MUTYH-associated polyposis (MAP). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2017]
Gene Details
Gene Symbol: MUTYH
Gene Name: MutY DNA Glycosylase
Chromosome: CHR1: 45794913-45806142
Locus: 1p34.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MUTYH FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MUTYH-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping