MUS81 FISH Probe
The MUS81 FISH probe is designed to hybridize to the MUS81 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MUS81-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MUS81-20-RE | 20 (40 μL) | 200 μL |  |
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| MUS81-20-GO | 20 (40 μL) | 200 μL |  |
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| MUS81-20-GR | 20 (40 μL) | 200 μL |  |
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| MUS81-20-AQ | 20 (40 μL) | 200 μL |  |
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| MUS81-20-DIG | 20 (40 μL) | 200 μL |  |
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| MUS81-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a structure-specific endonuclease which belongs to the XPF/MUS81 endonuclease family and plays a critical role in the resolution of recombination intermediates during DNA repair after inter-strand cross-links, replication fork collapse, and DNA double-strand breaks. The encoded protein associates with one of two closely related essential meiotic endonuclease proteins (EME1 or EME2) to form a complex that processes DNA secondary structures. It contains an N-terminal DEAH helicase domain, an excision repair cross complementation group 4 (ERCC4) endonuclease domain, and two tandem C-terminal helix-hairpin-helix domains. Mice with a homozygous knockout of the orthologous gene have significant meiotic defects including the failure to repair a subset of DNA double strand breaks. [provided by RefSeq, Jun 2017]
Gene Details
Gene Symbol: MUS81
Gene Name: MUS81 Structure-specific Endonuclease Subunit
Chromosome: CHR11: 65627871-65633914
Locus: 11q13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MUS81 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MUS81-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping