MUC16 FISH Probe
The MUC16 FISH probe is designed to hybridize to the MUC16 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MUC16-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MUC16-20-RE | 20 (40 μL) | 200 μL |  |
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| MUC16-20-GO | 20 (40 μL) | 200 μL |  |
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| MUC16-20-GR | 20 (40 μL) | 200 μL |  |
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| MUC16-20-AQ | 20 (40 μL) | 200 μL |  |
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| MUC16-20-DIG | 20 (40 μL) | 200 μL |  |
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| MUC16-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein that is a member of the mucin family. Mucins are high molecular weight, O-glycosylated proteins that play an important role in forming a protective mucous barrier, and are found on the apical surfaces of the epithelia. The encoded protein is a membrane-tethered mucin that contains an extracellular domain at its amino terminus, a large tandem repeat domain, and a transmembrane domain with a short cytoplasmic domain. The amino terminus is highly glycosylated, while the repeat region contains 156 amino acid repeats unit that are rich in serines, threonines, and prolines. Interspersed within the repeats are Sea urchin sperm protein Enterokinase and Agrin (SEA) modules, leucine-rich repeats and ankyrin (ANK) repeats. These regions together form the ectodomain, and there is a potential cleavage site found near an SEA module close to the transmembrane domain. This protein is thought to play a role in forming a barrier, protecting epithelial cells from pathogens. Products of this gene have been used as a marker for different cancers, with higher expression levels associated with poorer outcomes. [provided by RefSeq, May 2017]
Gene Details
Gene Symbol: MUC16
Gene Name: Mucin 16, Cell Surface Associated
Chromosome: CHR19: 8959519-9092018
Locus: 19p13.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MUC16 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MUC16-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping