MUC1 Break Apart FISH Probe
Empire Genomics’ MUC1 Break Apart FISH Probe is designed to flank the MUC1 gene and is typically used for detecting MUC1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MUC1BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| MUC1BA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| MUC1BA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| MUC1BA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| MUC1BA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| MUC1BA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| MUC1BA-20-ORGR | 20 (40 μL) | 200 μL |
|
|
| MUC1BA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| MUC1BA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]
Gene Details
Gene Symbol: MUC1
Gene Name: Mucin 1, Cell Surface Associated
Chromosome: CHR1: 155158299-155162706
Locus: 1q22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: MUC1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MUC1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping