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MTHFD1 Break Apart FISH Probe

Empire Genomics’ MTHFD1 Break Apart FISH Probe is designed to flank the MTHFD1 gene and is typically used for detecting MTHFD1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MTHFD1BA-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
MTHFD1BA-20-AQOR 20 (40 μL) 200 μL
MTHFD1BA-20-GOGR 20 (40 μL) 200 μL
MTHFD1BA-20-GORE 20 (40 μL) 200 μL
MTHFD1BA-20-GRGO 20 (40 μL) 200 μL
MTHFD1BA-20-GROR 20 (40 μL) 200 μL
MTHFD1BA-20-GRRE 20 (40 μL) 200 μL
MTHFD1BA-20-REGO 20 (40 μL) 200 μL
MTHFD1BA-20-REGR 20 (40 μL) 200 μL

Gene Summary

This gene encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: MTHFD1

Gene Name: Methylenetetrahydrofolate Dehydrogenase, Cyclohydrolase And Formyltetrahydrofolate Synthetase 1

Chromosome: CHR14: 64854758-64926725

Locus: 14q23.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: MTHFD1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: MTHFD1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping