MTHFD1 FISH Probe
The MTHFD1 FISH probe is designed to hybridize to the MTHFD1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MTHFD1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MTHFD1-20-RE | 20 (40 μL) | 200 μL |  |
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| MTHFD1-20-GO | 20 (40 μL) | 200 μL |  |
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| MTHFD1-20-GR | 20 (40 μL) | 200 μL |  |
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| MTHFD1-20-AQ | 20 (40 μL) | 200 μL |  |
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| MTHFD1-20-DIG | 20 (40 μL) | 200 μL |  |
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| MTHFD1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: MTHFD1
Gene Name: Methylenetetrahydrofolate Dehydrogenase, Cyclohydrolase And Formyltetrahydrofolate Synthetase 1
Chromosome: CHR14: 64854758-64926725
Locus: 14q23.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MTHFD1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MTHFD1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping