MTH2 FISH Probe
The MTH2 FISH probe is designed to hybridize to the MTH2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NUDT15-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| NUDT15-20-RE | 20 (40 μL) | 200 μL |  |
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| NUDT15-20-GO | 20 (40 μL) | 200 μL |  |
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| NUDT15-20-GR | 20 (40 μL) | 200 μL |  |
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| NUDT15-20-AQ | 20 (40 μL) | 200 μL |  |
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| NUDT15-20-DIG | 20 (40 μL) | 200 μL |  |
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| NUDT15-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified. [provided by RefSeq, Apr 2016]
Gene Details
Gene Symbol: NUDT15
Gene Name: Nudix Hydrolase 15
Chromosome: CHR13: 48611702-48621282
Locus: 13q14.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MTH2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NUDT15-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping