MTA1 Break Apart FISH Probe
Empire Genomics’ MTA1 Break Apart FISH Probe is designed to flank the MTA1 gene and is typically used for detecting MTA1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MTA1BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MTA1BA-20-AQOR | 20 (40 μL) | 200 μL |
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| MTA1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| MTA1BA-20-GORE | 20 (40 μL) | 200 μL |
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| MTA1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| MTA1BA-20-GROR | 20 (40 μL) | 200 μL |
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| MTA1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| MTA1BA-20-REGO | 20 (40 μL) | 200 μL |
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| MTA1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
Gene Details
Gene Symbol: MTA1
Gene Name: Metastasis Associated 1
Chromosome: CHR14: 105886185-105937057
Locus: 14q32.33
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MTA1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MTA1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping