MSH6 FISH Probe
The MSH6 FISH probe is designed to hybridize to the MSH6 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MSH6-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| MSH6-20-RE | 20 (40 μL) | 200 μL |  |
|
| MSH6-20-GO | 20 (40 μL) | 200 μL |  |
|
| MSH6-20-GR | 20 (40 μL) | 200 μL |  |
|
| MSH6-20-AQ | 20 (40 μL) | 200 μL |  |
|
| MSH6-20-DIG | 20 (40 μL) | 200 μL |  |
|
| MSH6-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]
Gene Details
Gene Symbol: MSH6
Gene Name: MutS Homolog 6
Chromosome: CHR2: 48010220-48034092
Locus: 2p16.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: MSH6 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MSH6-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping