MS4A2 Break Apart FISH Probe
Empire Genomics’ MS4A2 Break Apart FISH Probe is designed to flank the MS4A2 gene and is typically used for detecting MS4A2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
MS4A2BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
MS4A2BA-20-AQOR | 20 (40 μL) | 200 μL | ||
MS4A2BA-20-GOGR | 20 (40 μL) | 200 μL | ||
MS4A2BA-20-GORE | 20 (40 μL) | 200 μL | ||
MS4A2BA-20-GRGO | 20 (40 μL) | 200 μL | ||
MS4A2BA-20-GROR | 20 (40 μL) | 200 μL | ||
MS4A2BA-20-GRRE | 20 (40 μL) | 200 μL | ||
MS4A2BA-20-REGO | 20 (40 μL) | 200 μL | ||
MS4A2BA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. This gene encodes the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member is localized to 11q12, among a cluster of membrane-spanning 4A gene family members. Alternative splicing results in multiple transcript variants encoding distinct proteins. Additional transcript variants have been described but require experimental validation. [provided by RefSeq, Mar 2012]
Gene Details
Gene Symbol: MS4A2
Gene Name: Membrane Spanning 4-domains A2
Chromosome: CHR11: 59856136-59865940
Locus: 11q12.1
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|
Customer Publications
Product Details
Product: MS4A2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MS4A2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping