MRPS18A FISH Probe
The MRPS18A FISH probe is designed to hybridize to the MRPS18A gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MRPS18A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MRPS18A-20-RE | 20 (40 μL) | 200 μL |  |
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| MRPS18A-20-GO | 20 (40 μL) | 200 μL |  |
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| MRPS18A-20-GR | 20 (40 μL) | 200 μL |  |
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| MRPS18A-20-AQ | 20 (40 μL) | 200 μL |  |
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| MRPS18A-20-DIG | 20 (40 μL) | 200 μL |  |
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| MRPS18A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. A pseudogene corresponding to this gene is found on chromosome 3p. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010]
Gene Details
Gene Symbol: MRPS18A
Gene Name: Mitochondrial Ribosomal Protein S18A
Chromosome: CHR6: 43638933-43655549
Locus: 6p21.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MRPS18A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MRPS18A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping