MRPL22 Break Apart FISH Probe
Empire Genomics’ MRPL22 Break Apart FISH Probe is designed to flank the MRPL22 gene and is typically used for detecting MRPL22 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MRPL22BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MRPL22BA-20-AQOR | 20 (40 μL) | 200 μL |
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| MRPL22BA-20-GOGR | 20 (40 μL) | 200 μL |
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| MRPL22BA-20-GORE | 20 (40 μL) | 200 μL |
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| MRPL22BA-20-GRGO | 20 (40 μL) | 200 μL |
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| MRPL22BA-20-GROR | 20 (40 μL) | 200 μL |
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| MRPL22BA-20-GRRE | 20 (40 μL) | 200 μL |
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| MRPL22BA-20-REGO | 20 (40 μL) | 200 μL |
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| MRPL22BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: MRPL22
Gene Name: Mitochondrial Ribosomal Protein L22
Chromosome: CHR5: 154320632-154348971
Locus: 5q33.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MRPL22 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MRPL22-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping