MRE11 Break Apart FISH Probe
Empire Genomics’ MRE11 Break Apart FISH Probe is designed to flank the MRE11 gene and is typically used for detecting MRE11 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MRE11BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| MRE11BA-20-AQOR | 20 (40 μL) | 200 μL |
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| MRE11BA-20-GOGR | 20 (40 μL) | 200 μL |
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| MRE11BA-20-GORE | 20 (40 μL) | 200 μL |
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| MRE11BA-20-GRGO | 20 (40 μL) | 200 μL |
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| MRE11BA-20-GRRE | 20 (40 μL) | 200 μL |
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| MRE11BA-20-ORGR | 20 (40 μL) | 200 μL |
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| MRE11BA-20-REGO | 20 (40 μL) | 200 μL |
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| MRE11BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: MRE11
Gene Name: MRE11 Homolog, Double Strand Break Repair Nuclease
Chromosome: CHR11: 94512700-94415569
Locus: 11q21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MRE11 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MRE11-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping