MRD5 FISH Probe
The MRD5 FISH probe is designed to hybridize to the MRD5 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SYNGAP1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SYNGAP1-20-RE | 20 (40 μL) | 200 μL |  |
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| SYNGAP1-20-GO | 20 (40 μL) | 200 μL |  |
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| SYNGAP1-20-GR | 20 (40 μL) | 200 μL |  |
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| SYNGAP1-20-AQ | 20 (40 μL) | 200 μL |  |
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| SYNGAP1-20-DIG | 20 (40 μL) | 200 μL |  |
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| SYNGAP1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a Ras GTPase activating protein that is a member of the N-methyl-D-aspartate receptor complex. The N-terminal domain of the protein contains a Ras-GAP domain, a pleckstrin homology domain, and a C2 domain that may be involved in binding of calcium and phospholipids. The C-terminal domain consists of a ten histidine repeat region, serine and tyrosine phosphorylation sites, and a T/SXV motif required for postsynaptic scaffold protein interaction. The encoded protein negatively regulates Ras, Rap and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor trafficking to the postsynaptic membrane to regulate synaptic plasticity and neuronal homeostasis. Allelic variants of this gene are associated with intellectual disability and autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
Gene Details
Gene Symbol: SYNGAP1
Gene Name: Synaptic Ras GTPase Activating Protein 1
Chromosome: CHR6: 33387846-33421466
Locus: 6p21.32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MRD5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SYNGAP1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping