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MRD5 FISH Probe

The MRD5 FISH probe is designed to hybridize to the MRD5 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
SYNGAP1-20-OR  (Standard Design) 20 (40 μL) 200 μL
SYNGAP1-20-RE 20 (40 μL) 200 μL
SYNGAP1-20-GO 20 (40 μL) 200 μL
SYNGAP1-20-GR 20 (40 μL) 200 μL
SYNGAP1-20-AQ 20 (40 μL) 200 μL
SYNGAP1-20-DIG 20 (40 μL) 200 μL
SYNGAP1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a Ras GTPase activating protein that is a member of the N-methyl-D-aspartate receptor complex. The N-terminal domain of the protein contains a Ras-GAP domain, a pleckstrin homology domain, and a C2 domain that may be involved in binding of calcium and phospholipids. The C-terminal domain consists of a ten histidine repeat region, serine and tyrosine phosphorylation sites, and a T/SXV motif required for postsynaptic scaffold protein interaction. The encoded protein negatively regulates Ras, Rap and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor trafficking to the postsynaptic membrane to regulate synaptic plasticity and neuronal homeostasis. Allelic variants of this gene are associated with intellectual disability and autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]

Gene Details

Gene Symbol: SYNGAP1

Gene Name: Synaptic Ras GTPase Activating Protein 1

Chromosome: CHR6: 33387846-33421466

Locus: 6p21.32

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: MRD5 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: SYNGAP1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping