MRASAL FISH Probe
The MRASAL FISH probe is designed to hybridize to the MRASAL gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
RASAL1-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
RASAL1-20-RE | 20 (40 μL) | 200 μL | ||
RASAL1-20-GO | 20 (40 μL) | 200 μL | ||
RASAL1-20-GR | 20 (40 μL) | 200 μL | ||
RASAL1-20-AQ | 20 (40 μL) | 200 μL | ||
RASAL1-20-DIG | 20 (40 μL) | 200 μL | ||
RASAL1-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described [provided by RefSeq, Jul 2010]
Gene Details
Gene Symbol: RASAL1
Gene Name: RAS Protein Activator Like 1
Chromosome: CHR12: 113536623-113574044
Locus: 12q24.13
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|
Customer Publications
Product Details
Product: MRASAL FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RASAL1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping