MPZ Break Apart FISH Probe
Empire Genomics’ MPZ Break Apart FISH Probe is designed to flank the MPZ gene and is typically used for detecting MPZ rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MPZBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| MPZBA-20-AQOR | 20 (40 μL) | 200 μL |
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| MPZBA-20-GOGR | 20 (40 μL) | 200 μL |
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| MPZBA-20-GORE | 20 (40 μL) | 200 μL |
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| MPZBA-20-GRGO | 20 (40 μL) | 200 μL |
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| MPZBA-20-GRRE | 20 (40 μL) | 200 μL |
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| MPZBA-20-ORGR | 20 (40 μL) | 200 μL |
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| MPZBA-20-REGO | 20 (40 μL) | 200 μL |
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| MPZBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene is specifically expressed in Schwann cells of the peripheral nervous system and encodes a type I transmembrane glycoprotein that is a major structural protein of the peripheral myelin sheath. The encoded protein contains a large hydrophobic extracellular domain and a smaller basic intracellular domain, which are essential for the formation and stabilization of the multilamellar structure of the compact myelin. Mutations in this gene are associated with autosomal dominant form of Charcot-Marie-Tooth disease type 1 (CMT1B) and other polyneuropathies, such as Dejerine-Sottas syndrome (DSS) and congenital hypomyelinating neuropathy (CHN). A recent study showed that two isoforms are produced from the same mRNA by use of alternative in-frame translation termination codons via a stop codon readthrough mechanism. [provided by RefSeq, Oct 2015]
Gene Details
Gene Symbol: MPZ
Gene Name: Myelin Protein Zero
Chromosome: CHR1: 161274524-161279762
Locus: 1q23.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MPZ FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MPZ-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping