MPSPS FISH Probe
The MPSPS FISH probe is designed to hybridize to the MPSPS gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| VPS33A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| VPS33A-20-RE | 20 (40 μL) | 200 μL |  |
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| VPS33A-20-GO | 20 (40 μL) | 200 μL |  |
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| VPS33A-20-GR | 20 (40 μL) | 200 μL |  |
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| VPS33A-20-AQ | 20 (40 μL) | 200 μL |  |
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| VPS33A-20-DIG | 20 (40 μL) | 200 μL |  |
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| VPS33A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a tethering protein and a core subunit of the homotypic fusion and protein sorting (HOPS) complex. The HOPS complex and a second endosomal tethering complex called the class C core vacuole/endosome tethering (CORVET) complex, perform diverse functions in endocytosis including membrane tethering, RabGTPase interaction, activation and proofreading of synaptic-soluble N-ethylmaleimide-sensitive factor attachment receptor (SNARE) assembly to drive membrane fusion, and endosome-to-cytoskeleton attachment. The HOPS complex controls endosome maturation as well as endosome traffic to the lysosome. This complex is essential for vacuolar fusion and is required for adaptor protein complex 3-dependent transport from the golgi to the vacuole. The encoded protein belongs to the Sec1/Munc18 (SM) family of SNARE-mediated membrane fusion regulators. Naturally occurring mutations in this gene are associated with a novel mucopolysaccharidosis-like disease. [provided by RefSeq, Apr 2017]
Gene Details
Gene Symbol: VPS33A
Gene Name: VPS33A, CORVET/HOPS Core Subunit
Chromosome: CHR12: 122716093-122751068
Locus: 12q24.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MPSPS FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: VPS33A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping