MOCOS Break Apart FISH Probe
Empire Genomics’ MOCOS Break Apart FISH Probe is designed to flank the MOCOS gene and is typically used for detecting MOCOS rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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MOCOSBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
MOCOSBA-20-AQOR | 20 (40 μL) | 200 μL | ||
MOCOSBA-20-GOGR | 20 (40 μL) | 200 μL | ||
MOCOSBA-20-GORE | 20 (40 μL) | 200 μL | ||
MOCOSBA-20-GRGO | 20 (40 μL) | 200 μL | ||
MOCOSBA-20-GROR | 20 (40 μL) | 200 μL | ||
MOCOSBA-20-GRRE | 20 (40 μL) | 200 μL | ||
MOCOSBA-20-REGO | 20 (40 μL) | 200 μL | ||
MOCOSBA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes an enzyme that sulfurates the molybdenum cofactor which is required for activation of the xanthine dehydrogenase (XDH) and aldehyde oxidase (AO) enzymes. XDH catalyzes the conversion of hypoxanthine to uric acid via xanthine, as well as the conversion of allopurinol to oxypurinol, and pyrazinamide to 5-hydroxy pyrazinamide. Mutations in this gene cause the metabolic disorder classical xanthinuria type II which is characterized by the loss of XDH/XO and AO enzyme activity, decreased levels of uric acid in the urine, increased levels of xanthine and hypoxanthine in the serum and urine, formation of xanthine stones in the urinary tract, and myositis due to tissue deposition of xanthine. [provided by RefSeq, Apr 2017]
Gene Details
Gene Symbol: MOCOS
Gene Name: Molybdenum Cofactor Sulfurase
Chromosome: CHR18: 33767479-33848685
Locus: 18q12.2
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MOCOS FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MOCOS-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping