MMP11 Break Apart FISH Probe
Empire Genomics’ MMP11 Break Apart FISH Probe is designed to flank the MMP11 gene and is typically used for detecting MMP11 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
MMP11BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
MMP11BA-20-AQOR | 20 (40 μL) | 200 μL | ||
MMP11BA-20-GOGR | 20 (40 μL) | 200 μL | ||
MMP11BA-20-GORE | 20 (40 μL) | 200 μL | ||
MMP11BA-20-GRGO | 20 (40 μL) | 200 μL | ||
MMP11BA-20-GROR | 20 (40 μL) | 200 μL | ||
MMP11BA-20-GRRE | 20 (40 μL) | 200 μL | ||
MMP11BA-20-REGO | 20 (40 μL) | 200 μL | ||
MMP11BA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: MMP11
Gene Name: Matrix Metallopeptidase 11
Chromosome: CHR22: 24115035-24126503
Locus: 22q11.23
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|
Customer Publications
Product Details
Product: MMP11 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MMP11-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping