MMP11 FISH Probe
The MMP11 FISH probe is designed to hybridize to the MMP11 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MMP11-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MMP11-20-RE | 20 (40 μL) | 200 μL |  |
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| MMP11-20-GO | 20 (40 μL) | 200 μL |  |
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| MMP11-20-GR | 20 (40 μL) | 200 μL |  |
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| MMP11-20-AQ | 20 (40 μL) | 200 μL |  |
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| MMP11-20-DIG | 20 (40 μL) | 200 μL |  |
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| MMP11-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: MMP11
Gene Name: Matrix Metallopeptidase 11
Chromosome: CHR22: 24115035-24126503
Locus: 22q11.23
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MMP11 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MMP11-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping